A microenvironment-responsive FePt probes for imaging-guided Fenton-enhanced radiotherapy of hepatocellular carcinoma
创建时间：2022-03-11 16:24:49
Characterization of the synthesized FePt nanoprobes. a, b TEM images of FePt nanoprobes before (a) and after (b) PEGlyation. c Elements mapping of FePt nanoprobes (upper left: HAADF, upper right: Pt, lower left: Pt, lower right: merge). d XRD pattern of FePt nanoprobes. Red arrow-marked peaks belong to PEG. e The FTIR spectra of the bare FePt nanoprobes (black), mPEG-SH (red), and PEGylated FePt nanoprobes (blue). f ICP-OES data of FePt nanoprobes quantifying metal ratios
Ex vivo Fe2+ release and Fenton catalysis properties of FePt nanoprobes. a ICP-OES analyses of Fe2+ released from FePt nanoprobes (red) and Fe3O4 (black). b T2 relaxation rates of FePt nanoprobes incubated at various pH. c T1 relaxation rates of FePt nanoprobes incubated at various pH. d TEM images of FePt nanoprobes under various pH conditions. e MB absorbance after incubation with FePt nanoprobes (Fe concentration: 10 mM) and various concentrations of H2O2 at pH 5.4. f MB absorbance after incubation with various concentrations of FePt nanoprobes and H2O2 (40 mM) at 5.4 pH. g MB absorbance after incubation with FePt nanoprobes (Fe concentration: 10 mM) and H2O2 (40 mM) at various pH
